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Extremophile Protein Database
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Protein Information

 

Protein Details

ExProtDB ID
A.0000H0.05.H09
Name
PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1
Extreme Stable Behaviour
Halostable

Source Organism

ExProtDB ID
A.0000H0.05
Name
Halobacterium salinarum
Domain
Archaea
Extremophile Type
Halophile

Protein Function

Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. {ECO

Protein Classification

EC ID
E3
EC Number
3.6.5.3
Type
HYDROLASE

Optimum Physiochemical Conditions

Extreme-Stability ID
HA03
Optimum Condition
2.5-5.2M NaCl

Protein Sequence

UniProt KB ID
Molecular Weight (Da)
46638.0
Sequence Length
(amino acid numbers)
416
Sequence
MSEQDEVPSEDRRKYEFRKVIEELKDYEGSGTQLVTIYIPPDKQISDVVAHVTQEHSEASNIKSKQTRTNVQDALTSIKDRLRYYDTFPPDNGMVVFSGAVDSGGGRTDMVTEVLESPPQPIESFRYHCDSAFLTEPLAEMLGDKGLYGLIVLDRRESNVGWLKGKRVQPVKSAESLVPGKQRKGGQSAQRFARLRLEAIDNFYQEVAGMADDLFVPKRHEIDGILVGGPSPTKDEFLDGDYLHHELQDKVLGKFDVSYTDESGLSDLVDAGQAALAEADLMDDKSDMEEFFEELNGGKLATYGFEQTRRNLIMGSVDRLLVSEDLREDVVIYECPNDHEEYETIDRRNTSPEHTCSDCGEEATEVDREDAIDHLMSIADQRGTETHFISTDFEKGEQLLTAFGGYAGILRYSTGV

Protein Parameters

PID
H.P0004
Amino acid content (%)
 
Ala
5.529
Cys
0.962
Asp
9.856
Glu
10.096
Phe
3.846
Gly
8.173
His
2.404
Ile
4.327
Lys
4.808
Leu
8.413
Met
2.163
Asn
2.163
Pro
3.846
Gln
4.087
Arg
6.01
Ser
6.971
Thr
5.529
Val
6.971
Trp
0.24
Tyr
3.606
Amino acid class contents(%)
 
Tiny (A+C+G+S+T)
27.16
Small (A+C+D+G+N+P+S+T+V)
50.00
Aliphatic (A+I+L+V)
25.24
Aromatic (F+H+W+Y)
10.10
Non Polar (A+C+F+G+I+L+M+P+V+W+Y)
48.08
Polar (D+E+H+K+N+Q+R+S)
51.92
Charged (D+E+H+K+R)
33.17
Basic (H+K+R)
13.22
Acidic (D+E)
19.95
Intraprotein interactions (%)
 
Main Chain Main Chain Hydrogen Bonds
26.16
Main Chain Side Chain Hydrogen Bonds
7.63
Side Chain Side Chain Hydrogen Bonds
3.26
Hydrophonic Interactions
9.84
Ionic Interactions
3.26
Salt Bridges
1.30
Aromatic Aromatic Interactions
0.47
Aromatic Sulphur Interactions
0.06
Cation Pi Interactions
0.47
Disulphide Bridge Interactions
0.00

Protein Structure Details

RCSB PDB ID
Structure Resolution (A)
2
PMID
Authors
Karlsen, J.L., Kjeldgaard, M.
Journal
To be Published
Title
Archeal Release Factor Arf1 Contains a Metal Binding Domain
Volume
NA
Year
NA

Information Source

UniProt, RCSB PDB and BRENDA