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Extremophile Protein Database
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Protein Information

 

Protein Details

ExProtDB ID
A.0000H0.05.H11
Name
HALORHODOPSIN
Extreme Stable Behaviour
Halostable

Source Organism

ExProtDB ID
A.0000H0.05
Name
Halobacterium salinarum
Domain
Archaea
Extremophile Type
Halophile

Protein Function

Light-driven chloride pump.

Protein Classification

EC ID
E0
EC Number
-
Type
TRANSPORT PROTEIN

Optimum Physiochemical Conditions

Extreme-Stability ID
HA03
Optimum Condition
2.5-5.2M NaCl

Protein Sequence

UniProt KB ID
Molecular Weight (Da)
28874.0
Sequence Length
(amino acid numbers)
274
Sequence
MSITSVPGVVDAGVLGAQSAAAVRENALLSSSLWVNVALAGIAILVFVYMGRTIRPGRPRLIWGATLMIPLVSISSYLGLLSGLTVGMIEMPAGHALAGEMVRSQWGRYLTWALSTPMILLALGLLADVDLGSLFTVIAADIGMCVTGLAAAMTTSALLFRWAFYAISCAFFVVVLSALVTDWAASASSAGTAEIFDTLRVLTVVLWLGYPIVWAVGVEGLALVQSVGVTSWAYSVLDVFAKYVFAFILLRWVANNERTVAVAGQTLGTMSSDD

Protein Parameters

PID
H.P0001
Amino acid content (%)
 
Ala
14.234
Cys
0.73
Asp
3.285
Glu
2.19
Phe
3.65
Gly
8.759
His
0.365
Ile
5.474
Lys
0.365
Leu
13.869
Met
3.65
Asn
1.46
Pro
2.555
Gln
1.46
Arg
4.015
Ser
8.759
Thr
6.569
Val
12.409
Trp
3.65
Tyr
2.555
Amino acid class contents(%)
 
Tiny (A+C+G+S+T)
39.05
Small (A+C+D+G+N+P+S+T+V)
58.76
Aliphatic (A+I+L+V)
45.99
Aromatic (F+H+W+Y)
10.22
Non Polar (A+C+F+G+I+L+M+P+V+W+Y)
71.53
Polar (D+E+H+K+N+Q+R+S)
28.47
Charged (D+E+H+K+R)
10.22
Basic (H+K+R)
4.75
Acidic (D+E)
5.47
Intraprotein interactions (%)
 
Main Chain Main Chain Hydrogen Bonds
35.30
Main Chain Side Chain Hydrogen Bonds
7.36
Side Chain Side Chain Hydrogen Bonds
1.67
Hydrophonic Interactions
14.33
Ionic Interactions
0.39
Salt Bridges
0.28
Aromatic Aromatic Interactions
0.56
Aromatic Sulphur Interactions
0.11
Cation Pi Interactions
0.50
Disulphide Bridge Interactions
0.00

Protein Structure Details

RCSB PDB ID
Structure Resolution (A)
1.8
PMID
Authors
Kolbe, M., Besir, H., Essen, L.-O., Oesterhelt, D.
Journal
Science
Title
Structure of Light-Driven Chloride Pump Halorhodopsin at 1.8 A Resolution
Volume
288
Year
2000

Information Source

UniProt, RCSB PDB and BRENDA